M Michael Gromiha

Associate Professor

Ph.D, Bharathidasan University, India
M.Sc, Madurai Kamaraj University, India

Room No BT 105 (O)
Tel:91-44-2257-4138(O)
gromiha@iitm.ac.in
Dept of Biotechnology
IIT Madras

Research Interest
Lab Website
Publications
Honors and Awards

Research Interests

• Discrimination of membrane proteins based on structure and function
• Prediction of membrane spanning segments in alpha-helical and beta-barrel membrane proteins
• Recognition of protein folds
• Prediction of secondary and tertiary structures in globular proteins
• Conformational stability of proteins and nucleic acids
• Identification of important residues for protein stability and function
• Extreme stability of thermophilic proteins

• Prediction of protein stablity upon amino acid substitutions
• Medium and Long Range Interactions in Gobular Proteins
• Development of novel parameters/methods for understanding/predicting protein folding rates
• Development of thermodynamic and functional databases for proteins and interactions
• Structural analysis of proteins and their interactions
• Elastic characters of DNA/RNA and importance to binding specificity
• Computer simulation of protein-DNA interactions
• Recognition mechanism for protein-protein, protein-nucleic acid, protein-carbohydrate and protein-ligand interactions